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L-Dopa (90) Veggie Caps

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Sufferers of muscle tension, restless leg, or stress related shortness of breath? You can find relief with L-Dopa.

Capsules per bottle: 90

Availability: In stock



L-DOPA crosses the protective blood–brain barrier, whereas dopamine itself cannot. Thus, L-DOPA is used to increase dopamine concentrations in the treatment of Parkinson's disease and dopamine-responsive dystonia. This treatment was made practical and proven clinically by George Cotzias and his coworkers, for which they won the 1969 Lasker Prize. Once L-DOPA has entered the central nervous system, it is converted into dopamine by the enzyme aromatic L-amino acid decarboxylase, also known as DOPA decarboxylase. Pyridoxal phosphate (vitamin B6) is a required cofactor in this reaction, and may occasionally be administered along with L-DOPA, usually in the form of pyridoxine.

Besides the central nervous system, L-DOPA is also converted into dopamine from within the peripheral nervous system. The resulting hyperdopaminergia causes many of the adverse side effects seen with sole L-DOPA administration. To bypass these effects, it is standard clinical practice to coadminister (with L-DOPA) a peripheral DOPA decarboxylase inhibitor (DDCI) such as carbidopa (medicines combining L-DOPA and carbidopa are branded as Lodosyn, Sinemet, Parcopa, Atamet, and Stalevo) or with a benserazide (combination medicines are branded Madopar or Prolopa), to prevent the peripheral synthesis of dopamine from L-DOPA. Coadministration of pyridoxine without a DDCI accelerates the peripheral decarboxylation of L-DOPA to such an extent that it negates the effects of L-DOPA administration, a phenomenon that historically caused great confusion.

In addition, L-DOPA, co-administered with a peripheral DDCI, has been investigated as a potential treatment for restless leg syndrome. However, studies have demonstrated "no clear picture of reduced symptoms"

Serving Size - 2 Veg Capsules
Serving Per Container - 45

Amount per serving%DV
Vevet Bean Extract (Mucuna pruriens)
(Seed) (min. 15% L-DOPA, naturally occuring)

*Daily Value not established.

Cellulose (capsule), Cellulose Powder, Stearic Acid (vegetable source) and Magnesium Stearate (vegetable source).

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens

Take 1 to 2 capsules with a meal. Best when taken early in the day.

Dopamine is a neurotransmitter that promotes enjoyment and interest in life. * With 15% L-DOPA (the immediate precursor of dopamine), L-DOPA helps the body with what it needs to make this important neurotransmitter. *Mucuna pruiens, commonly known as Velvet Bean, has been used in the traditional Ayurvedic system in India for thousands of years.

*These statement have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.